“I have no problem with coffee but don’t drink it first thing in the morning,” Gibson says, “Wait until you actually need it.” Exercise first to boost your mood and energy, she adds. Caffeine is chemically addictive. Many consumers may be unaware of their physical dependence because their frequent habitual consumption precludes a period of sustained abstinence (e.g. 2 days), according to John Hopkins Medicine. Symptoms of withdrawal from both include irritability, headaches, fatigue, anxiety, vomiting, and stiffness.