Long used in traditional Indian cuisine as well as in Ayurvedic treatments, this spice from the root Curcuma longa is more than just a flavorful seasoning in curries. Reviews by the University of California have unearthed a body of research on this golden yellow root, and at least six human trials have shown it is safe for adult consumption and has some anti-inflammatory effects. Researchers believe it may work by restricting compounds involved in inflammation. Research reviewed by the NIH has also indicated that turmeric may also help ease upset stomachs, and alleviate the pain of osteoarthritis, with research from the Siriraj Hospital in Thailand indicating it may be just as effective and safe as ibuprofen in reducing osteoarthritic knee pain.