Many cancer patients receive powerful chemotherapy drugs that alter their blood counts and peripheral nerves, causing fatigue. Studies show that patients benefit from exercise and movement during treatment, but it’ss not always as easy to do as it was before chemo. Even basic training routines can be a lot more difficult to do, depending on how active the patient was before the therapy, Karen Hock, a physical therapist at The Ohio State University Comprehensive Cancer Center. Even walking can be a challenge for some. “Exercise will help you dial back to a physical level that’s appropriate for you."