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This is the longest – 118 miles – and best known scenic byway in the state. It is named Cherokee Foothills because it runs through the foothills found at the base of the majestic Blue Ridge Mountains which were the ancestral home of the Cherokees, according to SCDOT. Starting in Cherokee County, it runs along SC 11 all the way through Spartanburg, Greenville, Pickens and Oconee Counties to the west.