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Diet sodas trick the brain by triggering its “awards” regions, causing “metabolic derangements.” That basically means that you end up eating more or changing your diet in an unhealthy way, eventually leading to the diseases you are trying to avoid, such as obesity and diabetes. Another study has linked artificial sweeteners to a change in gut microbes, increasing the risk of Type 2 diabetes. Excessive drinking causes chronic inflammation of the pancreas. As a result, it can’t secrete insulin properly, leading to diabetes.