Human noroviruses are a leading cause of acute, nonbacterial gastroenteritis worldwide. Vaccine development has been worked on for years, but the lack of a cell culture system and smaller animal model has delayed progress. However, just recently, a norovirus vaccine has appeared promising in children aged 1-8 years in an interim analysis of an ongoing phase 2 study. The vaccine contains virus-like particle antigens from norovirus strains GI.1 and GII.4c, which together account for most of the norovirus illnesses.